pAI

Principal (Agentic) Investigator

Developed by the Poggio Lab team at MIT

We're building pAI, a multi-agent AI system that turns research hypotheses into high-quality, literature-grounded, experiment-backed papers with minimal human steering.

Why pAI

Current AI systems require on the order of 102 to 103 prompts to go from a research idea to a written paper. pAI aims to reduce this to up to 10 human interactions.

This is not about fully automating research or replacing human creativity. pAI focuses on the rigorous establishment of ideas: matching theory with experiments, distinguishing correlation from causation, proposing parallel explanations and testing them. The human provides the idea. The system does the structured work of turning it into a solid manuscript.

5-Minute Quickstart to MSc

Cost: ~$2-10

Time: 15-40 min

Requires: one API key

quickstart.sh
# 1. Bootstrap environment (one-time, ~5 min)
./scripts/bootstrap.sh researchlab minimal

conda activate researchlab

# 2. Set your API key (only one provider needed)
cp .env.example .env
echo "ANTHROPIC_API_KEY=your_key_here" >> .env

# 3. Validate setup without spending tokens
python launch_multiagent.py --task "test" --dry-run

# 4. Run the included quickstart example (~$3)
python launch_multiagent.py \
  --task "$(cat examples/quickstart/task.txt)" \
  --output-format markdown \
  --no-counsel \
  --no-log-to-files

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© 2026 Mahmoud Abdelmoneum, Pierfrancesco Beneventano, Tomaso Poggio.